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Atomic details of protein ‘droplets’ may shed light on ALS
Researchers have determined the atomic interactions that stabilize the liquid yet “condensed” phase of FUS, an important phase-changing protein linked to severe cases of amyotrophic lateral sclerosis...
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1 method may prevent brain cell death in several diseases
Many neurodegenerative diseases have a common feature that may leave them vulnerable to the same treatment, researchers report. “We’ve identified a potential new way to reduce nerve-cell death in a...
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Turtle spine signals reveal how movement starts
Our bodies most likely generate and maintain movement through a network of cells, rather than from a single point, researchers report. “Most movements are actually generated in the spinal cord....
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Overcharged cell process clears dangerous ALS ‘junk’
A surprising discovery about the aggregates that build up in patients with amyotrophic lateral sclerosis, also known as ALS or Lou Gehrig’s disease, could pave the way for a new kind of intervention....
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Broken ‘rules’ lead to protein clumps in diseases like ALS
New research uncovers the underlying rules that, when broken, contribute to neurodegenerative diseases such as ALS. Clumps of proteins inside cells are a common thread in many neurodegenerative...
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Brain cell protection may also regulate your sleep
A biological mechanism that scientists believe protects brain cells from neurodegenerative diseases such as Alzheimer’s and Parkinson’s may also have a role in regulating sleep, according to a new...
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Blood plasma analysis could spot signs of ALS
Analysis of blood plasma could help identify diagnostic and prognostic biomarkers for amyotrophic lateral sclerosis, according to new research. The work sheds further light on a pathway involved in...
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‘Barcode’ IDs special glial cells in the brain
Researchers have identified important molecules that can help identify specific glial cells integral to synapses in the brain. While the brain is composed of two types of cells, glia tend to receive...
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Drug shows promise for fighting rare ALS
An experimental drug for a rare, inherited form of amyotrophic lateral sclerosis has shown promise in a phase 1/phase 2 clinical trial, researchers report. The trial indicated that the experimental...
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Team links gut bacteria to neurodegenerative diseases
Researchers have established, for the first time, a link between specific gut bacteria species and physical manifestations of neurodegenerative diseases. Neurodegenerative diseases such as Alzheimer’s,...
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